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Research

In recent years, Virtual Reality (VR) has emerged as a transformative tool with profound implications across diverse domains, notably Healthcare and Training. At Khora, we proudly engage in pioneering as frontiers of VR and Augmented Reality (AR) applications by participating in research projects across a wide range of use cases. Below you will find a list of the research projects and publications that Khora has participated in.

Mads Nathaniel Lopes

Mads Nathaniel Lopes

Business Developer

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Social Anxiety VR Exposure
Status: Ongoing
Mental Health / Social Anxiety
Research Title: SoReal
Partners: Region H Psykiatri, VIRTU

The SO REAL project is so far the world’s largest trial investigating the use of Virtual Reality (VR) in the treatment of social anxiety disorder. Overall, the project will contribute with knowledge about the efficacy and feasibility of treating social anxiety with VR exposure

Controlled Bullying Scenario
Status: Published
Mental Health / Schizophrenia
Research Title: SoReal
Partners: VIRTU, Louise Birkedal Glenthøj

investigate if avatars resembling sources of hallucation can reduce their impact. Khora created a VR simulation using 3D avatars and motion capture tech to depict a controlled bullying scenario

VR Dialogue Therapy for Eating Disorders
Status: Ongoing
Mental Health / Schizophrenia
Research Title: Eating Disorders
Partners: VIRTU, Louise Birkedal Glenthøj

Engage the patient in a dialogue with the eating disorder voice in order to reduce the power of the inner voice

Comparison of Pain Management for Children
Status: Published
Somatic / Needle Procedures in Children
Research Title: Comfort XR2
Partners: 

Comparing VR games with numbing cream and tablet/smartphone games for pain management during needle procedures

ABCDE on Neonates
Status: Ongoing
Somatic / ABCDE
Research Title: Resuscitation PhD Project
Partners: 

Investigate if an animated and interactive VR environment can improve the performance of ABCDE procedures on neonatals

Better QoL for elderlies
Status: Published
Mental Health / Social Anxiety
Research Title: Khora Care
Partners: 

To enhance the life quality of eldery people and individuals with dementia through VR-experiences

VR Therapy for Schizophrenia
Status: Published
Mental Health / Schizophrenia
Research Title: The Challenge Trial
Partners: VIRTU, Louise Birkedal Glenthøj

investigate if avatars resembling sources of hallucation can reduce their impact. Khora created a VR simulation using 3D avatars and motion capture tech to depict a controlled bullying scenario

 

Cerebral Palsy VR Task
Status: Ongoing
Mental Health / Schizophrenia
Research Title: The Challenge Trial
Partners: Region H, Jonstrupvang Bosted, Copenhagen University, Elsass-fonden

investigate whether Khora’s VR game can have a positive long-term impact for a patient with CP. 

Social Anxiety in Adults & Biofeedback System
Status: Ongoing
Mental Health / Social Anxiety
Research Title: The Challenge Trial
Partners: Telepsykiatrisk center, Center for Digital Psykiatri, Region Syddanmark

Develop, evaluate and implement VR with an automated biofeedback system for social anxiety in adults

VR Entertainment in Psychiatric Ward
Status: Ongoing
Mental Health / Leisure
Research Title: Leisure VR in Closed Psychiatric Ward
Partners:

Comparison of VR-assisted exposure therapy for auditory hallucinations vs supportive counselling in people with psychosis. 

ABCDE skill-assessment
Status: Published
Somatic / ABCDE
Research Title: Skill-assessment with VR in Emergency Medicine
Partners:

Investigate efficacy of using 360-degree VR videos with multiple choice questions for skill-assessment in emergency medicine

A Vision of the Future
Status: Ongoing
Leisure
Research Title: REWORK
Partners:

This project seeks a vision of the future that integrates hybrid work experiences, digital tools, and physical workspaces

Pain Distraction for Children
Status: Ongoing
Somatic / Needle procedures
Research Title: Comfort XR1
Partners: Region H videnscenter for børnesmerter

This study focuses on enhancing pain management for hospitalized children, particularly during needle procedures. By introducing a captivating 3D interactive VR game as a distraction, the research aims to alleviate anxiety and pain

VR Therapy for Schizophrenia
Status: Published
Mental Health / Schizophrenia
Research Title: The Challenge Trial Study Protocol
Partners: Region H, Jonstrupvang Bosted, Copenhagen University, Elsass-fonden

Comparison of VR-assisted exposure therapy for auditory hallucinations vs supportive counselling in people with psychosis. 

Screening for Birth Depression
Status: Published
Mental Health / Birth Depression
Research Title: Screening for Birth Depression
Partners: Region H Psykiatri, NEAD

Identify women who are at risk of developing postpartum depression, so that an intervention can be initiated

Bipolar Disorder Emotional Regulation
Status: Published
Mental Health / Bipolar Disorder
Research Title: Emotional Regulation
Partners: 

This study explores emotion regulation in bipolar disorder (BD) and unaffected relatives (UR) using a unique approach – a virtual reality (VR) task.

Diagnosing Social Anxiety
Status: Ongoing
Mental Health / Social Anxiety
Research Title: iSCAN
Partners:

Examine whether gaze behavior is a behavioral marker for social anxiety disorder and if VR eye-tracking can be used as a diagnostic tool

Evaluating VR exposure
Status: Published
Mental Health / 
Research Title: Khora Exposure
Partners: 

Evaluation of VR exposure therapy.

Ongoing

Published

Titel: SoReal

Partner: Region H Psykiatri, VIRTU

Status: Ongoing

Titel: Via 11

Partner: Region H Psykiatri

Status: Published

Link for paper

The SO REAL project is so far largest trial investigating the use of Virtual Reality (VR) in the treatment of social anxiety disorder. Overall, the project will contribute with knowledge about the efficacy and feasibility of treating social anxiety with VR exposure

Phase 11 is part of a larger study called The Danish High Risk and Resilience Study, focusing on understanding how upbringing and genetics affect children’s mental health. Khora created a Virtual Reality simulation using 3D avatars and Motion Capture technology to depict a controlled bullying scenario.”

Titel: Cerebral Palsy

Partner: Region H, Jonstrupvang Bosted, Copenhagen University, Eliasfonden

Status: Ongoing

Titel: The Challenge Trial

Partner: VIRTU, Louise Birkedal Glenthøj

Status: Published

Link for paper

Creating a custom-made VR game that enables more engaging exercises for citizens suffering from cerebral palsy, with the goal of investigating whether the VR game can have a positive impact on the amount of exercise and can lead to long-term improvement in citizens’ motor skills.

This research addresses auditory hallucination challenges in schizophrenia. The CHALLENGE project employs novel virtual reality avatar therapy, enabling direct dialogue with troubling voices. Patients create avatars resembling sources of hallucinations, gradually reducing their impact. Tested in Danish regions, this randomized trial could enhance outpatient psychiatric care.

Titel: Eating Disorders

Partner: VIRTU, Louise Birkedal Glenthøj

Status: Ongoing

Titel: The Challenge Trial Study Protocol

Partner: VIRTU, Louise Birkedal Glenthøj

Status: Published

Link for paper

The Dialogue study is the first of its kind to investigate the effect of 7 sessions of VR-based therapy in which the patient engages in a dialogue with the “eating disorder voice”.This treatment approach has proven highly effective in treating auditory hallucinations in psychosis. We expect VR-treatment to be able to significantly improve symptoms, functioning, and quality of life along with being cost-effective.

The effects of a virtual reality-assisted exposure therapy for persistent auditory hallucinations versus supportive counselling in people with psychosis: study protocol for a randomized clinical trial.

Titel: VR8

Partner: Telepsykiatrisk Center, Center for Digital Psykiatri, Region Syddanmark

Status: Ongoing

Titel: Comfort XR1

Partner: Region H Videns-center for Børnesmerter

Status: Published

Link for paper

The vision for VRaid (VR8)  is to develop, evaluate and implement Virtual Reality with an automated biofeedback system for treatment of social anxiety in adults.

This study focuses on enhancing pain management for hospitalized children, particularly during needle procedures. By introducing a captivating 3D interactive VR game as a distraction, the research aims to alleviate anxiety and minimize pain

Titel: Screening for Birth Depression

Partner: Region H Psykiatri, NEAD

Status: Ongoing

Titel: Comfort XR2

Partner: Region H Videns-center for Børnesmerter

Status: Published

Link for paper

Testing the feasibility of using VR to screen pregnant women for postpartum depression, with the aim of identifying women who are at risk of developing postpartum depression, so that an intervention can be initiated.

This study explores how virtual reality (VR) games can assist children aged 4 to 7 during medical procedures like needles. We’re comparing VR with usual methods like numbing cream and tablet/smartphone games.

Titel: Leisure VR for Lukkede afdeling 

Partner: Region H Psykiatri, VIRTU

Status: Ongoing

Titel: Emotion Regulation

Partner: Region H Psykiatri, NEAD

Status: Published

Link for paper

The purpose of this experiment is to investigate whether these virtual reality-based experiences are effective in reducing the use of necessity-based medication and coercive measures in a psychiatric department, as well as whether they can reduce stress/discomfort and increase satisfaction with a psychiatric hospitalization.

This study explores emotion regulation in bipolar disorder (BD) and unaffected relatives (UR) using a unique approach – a virtual reality (VR) task.

Titel: Ressusitation PhD Project

Partner: Region H Børn & Unge Afdelingen

Status: Ongoing

Titel: Using VR Head-Mounted Displays to assess skills in emergency medicine

Partner: CAMES

Status: Published

Link for paper

This study investigates if Using an interactivetive animated VR enviroment to train helathcare professional i life saving ABCDE procedures on neonatals is feasible and to what extent it can replace real life training.

This study aimed to gather validity evidence for using 360-degree VR videos with integrated multiple-choice questions to assess emergency medicine skills.

Titel: iSCAN

Partner: VIRTU

Status: Ongoing

Titel: Khora Care

Partner: Patient@Home

Status: Published

Link for paper

The iSCAN project PhD student Fatime Zeka is examining gaze behaviour in social anxiety disorder (SAD) using a virtual reality eye-tracking paradigm. The aim of the project is to examine whether gaze behavior is a behavioral marker for SAD and to examine the potential of VR eye-tracking as an objective screening tool for SAD that may aid early detection.

Khora Care is a solution with the purpose of enhancing the life quality of elderly people and individuals with dementia through Virtual Reality experiences. 

Titel: REWORK

Partner: Direc – Digital Research Center Denmark

Status: Ongoing

Titel: Khora Exposure

Partner: Århus Kommune

Status: Published

Link for paper

Remote and hybrid work will certainly be part of most work practices, but what should these future work practices look like? Should we merely attempt to fix what we already have or can we be bolder and design a different kind of future workplace? Together with companies, this project seeks a vision of the future that integrates hybrid work experiences.

Samlet Evaluering af VR-Eksponering i MSB